Evaluation of apoptosis and immunohistochemical expression of the apoptosis-related proteins in mesothelioma.

In conclusion, apoptosis is an uncommon event in mesothelioma and low mean cleaved caspase-3 index, suggesting the role of low activation of caspase-3 for inhibition of apoptosis. High expression of survivin in mesothelioma may play a role in inhibition of apoptosis. PMID: 20632685 [PubMed - indexed for MEDLINE] (Source: Hiroshima Journal of Medical Sciences)

from MedWorm: Mesothelioma http://www.medworm.com/index.php?rid=157649566&cid=c_409_22_f&fid=41880&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F20632685%3Fdopt%3DAbstract