Conclusion: In cell adhesion of mesothelioma cells, AQP1 inhibition is cell-type dependent while EnaC inhibition is cell-type and extracellular matrix-type dependent. These results render AQP1 and/or EnaC drug targeting worth investigating in MPM pathobiology. (Source: European Respiratory Journal)
from MedWorm: Mesothelioma http://www.medworm.com/index.php?rid=146296744&cid=c_409_40_f&fid=40789&url=http%3A%2F%2Ferj.ersjournals.com%2Fcgi%2Fcontent%2Fshort%2F46%2Fsuppl_59%2FPA4351%3Frss%3D1
The role of aquaporin-1 (AQP1) and amiloride sensitive epithelial sodium (ENaC) in cell adhesion of mesothelioma cells is cell and extracellular matrix type dependent
ad
Enregistrer un commentaire